Skip to content
RESEARCH USE ONLYFor research purposes onlyMÉXICO
Peptides MEX

Neuroscience / Research index

Semax

Semax features in experimental studies of the brain’s response to ischemia. Molecular findings need to remain connected to their research model.

Names used in the literature: Semax · ACTH(4–7)PGP · MEHFPGP

Read the evidence and its sources ↓

Semax 5 mg

Presentation
5 mg
Catalog reference
PMX-SEMX-10
MX$658 MXNReference price · to be confirmed
View my selection ↗

Availability and documentation await confirmation. Listed quantities identify catalog presentations, not instructions for use.

The identity worth retaining

Semax is a synthetic peptide with the sequence Met-Glu-His-Phe-Pro-Gly-Pro, also designated ACTH(4–7)PGP. These identifiers help make a literature search specific.

Sources: [2]

Genes in a rat model

A 2014 paper compared gene expression after permanent occlusion of a cerebral artery in rats. It described changes associated with immune and vascular processes. This measures brain tissue in an experimental injury setting; it does not demonstrate improved concentration or memory in healthy people.

Sources: [1]

Proteins in a different experimental design

In 2021, a rat ischemia-reperfusion model showed increased active CREB in subcortical regions and reduced MMP-9 in adjacent cortex. These are regional molecular measurements, not patient functional-recovery outcomes.

Sources: [2]

Questions about this reference

Do the cited studies evaluate memory in healthy people?

No. Both selected papers investigate rat models of cerebral ischemia.

[1][2]

Did both papers measure the same thing?

No. The first examined gene expression after permanent ischemia; the second examined proteins in an ischemia-reperfusion model.

[1][2]

Sources and original reading

  1. The peptide semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia: genome-wide transcriptional analysis
  2. Brain Protein Expression Profile Confirms the Protective Effect of the ACTH(4–7)PGP Peptide (Semax) in a Rat Model of Cerebral Ischemia–Reperfusion

Content updated: . How this content is prepared and checked.

Explore Neuroscience ↗