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Peptides MEX

Peptides MEX / Glossary

Solid support: where a peptide chain is assembled

In synthesis, solid phase describes where the growing chain remains attached.

Updated · Sources and editorial standards

The support during assembly

A solid support, usually a functionalized resin, holds the growing peptide. This allows the support to be separated from reagents in the liquid phase. It does not mean the finished product should retain the resin.

Sources: [1]

Three different meanings to keep separate

Peptide powder describes physical form; solid-phase synthesis describes a strategy; stationary phase describes a chromatographic role. A listing marked SPPS does not establish final presentation or purity.

Sources: [1]

Questions about this reference

Does solid phase mean the peptide is lyophilized?

No. One expression describes a synthesis support and the other a drying process.

[1]

Sources and original reading

  1. Bachem: Introduction to Peptide Synthesis Methods

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