Peptides MEX / Glossary
Potency: comparing concentrations and responses
A potency comparison needs a defined effect and the conditions in which it was measured.
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How much is needed for an effect
In pharmacology, potency compares the amount or concentration required to produce a defined effect. Under comparable conditions, a lower EC50 indicates greater potency in that assay. Efficacy describes another aspect of response; purity describes composition.
Sources: [1]
Compare equivalent assays
Two EC50 values are not directly equivalent if the cellular system or measured response differs. Copy the assay and units alongside the value. Greater potency in one test does not establish universal superiority or necessarily greater efficacy.
Sources: [1]
Questions about this reference
Does 99% purity mean 99% potency?
No. Purity percentage and potency measurement answer different questions.
Sources and original reading
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