Peptides MEX / Glossary
Pharmacokinetics: concentration and change over time
Pharmacokinetics organizes time-dependent information about a substance and its transformation products in the body.
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The course of a substance
Pharmacokinetics studies uptake, distribution, transformation and elimination. It may describe concentrations over time in biological samples. Pharmacodynamics instead examines actions and responses in the biological system.
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Recognizing the result type
A plasma-concentration-versus-time plot is pharmacokinetic. A biological-signal-versus-concentration plot addresses a pharmacodynamic response. Retain species, sample matrix and conditions when summarizing a study; a curve alone does not prescribe a use.
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Questions about this reference
Does measuring concentration establish benefit?
No. Concentration measures exposure; benefit requires outcomes suited to that question.
Sources and original reading
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