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Peptides MEX

Peptides MEX / Glossary

Melanocortin system: different peptides and receptors

A signaling system groups related participants, but each still requires precise identification.

Updated · Sources and editorial standards

Ligands, receptors and pigment

The POMC precursor yields peptides including ACTH and forms of MSH involved in melanocortin signaling. Receptors such as MC1R and MC4R have different roles. Melanin names a pigment; it is not a synonym for melanocortin or receptor.

Sources: [1]

Retain the receptor subtype

A finding about MC1R does not automatically transfer to MC4R. When summarizing research, record the receptor, ligand and tissue or model. Membership in one system does not establish an identical response across its components.

Sources: [1]

Questions about this reference

Does melanocortin system mean a single peptide?

No. It includes several related peptides and receptors; the particular molecule needs specification.

[1]

Sources and original reading

  1. NIH / MedlinePlus Genetics: POMC gene

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